Natural & Mathematical Sciences
Michael I. Nishimura ’80 BA ’84 MS ’89, PhD Biological Sciences
Michael I. Nishimura ’80 BA ’84 MS ’89, PhD Biological Sciences, has devoted his career to developing novel immunologic approaches for cancer therapy and is recognized for his talents as a scientific mentor. Building upon his strong genetics and immunology training acquired at UMBC, he pioneered the use of retroviral vectors encoding T cell receptor (TCR) genes to engineer an individual’s own lymphocytes to be able recognize and control the patients cancer cells or virus-infected cells. The first clinical trial using TCR gene modified T cells was conducted in Denmark using one of Dr. Nishimura’s TCR’s targeting the melanoma protein MART-1. Dr Nishimura serves as the Vice Chair for Research in the Department of Surgery at the Medical University of South Carolina and has assembled a strong clinical and scientific team committed to bringing this and other novel cellular therapies to the clinic.